January 2019 Kentucky Lake Section Meeting
Murray State University
1212 Jesse D Jones Hall
Thursday, January 24, 2019
Dinner 6:00 pm
Presentation 7:00 pm
Dinner: Massaman (chicken) and panang (Vegetarian) curry, jasmine rice, fruit tray, cookies ($10, $5 for students)
Program: Phosphines as Mild Reducing Agents: Synthesis of Alkenes from Alkynes
Dr. Rachel Whittaker, Assistant Professor at Murray State University
Few mild and selective alkyne reduction methods have been reported, but the resulting alkenes are important functional groups found in many biologically and industrially useful compounds. Thus, a mild and tunable partial reduction of alkynyl carbonyls was developed, utilizing readily available phosphines as the reductants. Tuning of the reaction conditions allowed for either the cis- or trans-diastereomer to be formed with high selectivity. These reaction conditions demonstrated good functional group tolerance and high yields.
Rachel grew up in Cartersville, GA before obtaining her B.S. degree in Biochemistry from Abilene Christian University in 2011. She received her Ph.D. in Chemistry from the University of Texas at Austin in 2016 with Professor Guangbin Dong working on rhodium-catalyzed C-C activation. Currently, she is an Assistant Professor at Murray State University where her research is focused on the development of mild redox methodologies.
Children are welcome and will attend a special Science Center during the program.