Meeting September 20th

September 2018 Kentucky Lake Section Meeting
@
Union University
1050 Union University Drive
Jackson, TN 38305

Thursday, September 20th, 2018
Dinner @ 6:00 pm, Presentation @ 7:00 pm

All events will be held in the Carl Grant Events Center on campus
Directions and maps:  http://www.uu.edu/about/map/index.htm#Directions

From U.S. Highway 45 Bypass, take Union University Drive west to Walker Road. Turn left on Walker Road. The Grant Center is on your left after passing the Welcome House gate and student housing on the left.

Dinner: Choice of Greek Chicken or Beef Brisket, Salad, Cheesy mashed potatoes, mixed vegetables, and Chocolate Explosion with ice cream

Program: Learning to Abandon Assumptions and to Ask the Right Questions or A Mild, Metal-Free Method for the Synthesis of Fused Azaheteroaromatics

Dr. E. Blake Watkins, Professor of Medicinal Chemistry,
Union University College of Pharmacy

Bring your children to attend the Science Center!

Abstract:

Carbolines and fused-pyridine heterocycles are ubiquitous structural motifs prevalent in natural products, pharmaceuticals, agrochemicals, materials and ligand scaffolds, thus highlighting the significance of such structures. Among the isomeric α-, β-, γ-, and δ-carbolines, the most abundant framework in nature is β-carboline. β-Carboline-containing structures possess a wide array of pharmacological properties, including anti-inflammatory, anti-Alzheimer, antimalarial, antibacterial, antitumor, anti-HIV and others. Current procedures require multi-step syntheses or extended preparation of starting materials in order to prepare these isomeric structures.  Our interest in metal-catalyzed, C-H functionalization reactions compelled us to explore the synthesis of these agents in a much more economical manner, particularly in regard to the use of metal catalysts/additives and the number of synthetic steps.  The current status of this project and its application to the synthesis of a wide variety of variously substituted pyridines will be presented, with particular attention paid to agents of pharmacological interest

Speaker Biography:

Blake Watkins speaker photo

Blake Watkins serves as Professor of Medicinal Chemistry and Founding Chair of Pharmaceutical Sciences in the College of Pharmacy at Union University.  He completed his Bachelor of Science in Mathematics and Chemistry at Union and received his PhD in Chemistry from the University of Georgia under the direction of Professor Robert S. Phillips.  After doing postdoctoral work at the University of Mississippi School of Pharmacy in the Department of Medicinal Chemistry under Professor Mitchell A. Avery, he worked as a Research Scientist and Research Assistant Professor in drug discovery and natural products synthesis.  In 2008, he returned to Union to help start the College of Pharmacy.  His current research interests include synthetic method development with application to natural products and drug discovery.

Click link for pictures of the event.

 

March 2018 – Message from the Chair

Greetings KLS Members,

This month we will be hearing from Dr. Elizabeth Thomas, a visiting professor at Berea College. Dr. Thomas is a graduate of the University of Kentucky and spent 6 years working as an organic chemist at Eli Lilly. Those of you who enjoy pharmaceutical chemistry won’t want to miss this event!
See you next week,

Genessa

Don’t forget: The 41st Annual Area Collegiate Chemistry Meeting is April 7th at UT-Martin.  Deadline to submit for oral or poster presentation is April 3rd.

February 2018 – Message from the Chair

Greetings KLS Members!

February may be the shortest month in the calendar, but there’s double the opportunity for you to meet and mingle with other chemistry enthusiasts this month!

For our regularly scheduled meeting, we’ll be hearing from Dr. Bikram Subedi, professor at Murray State University.  Dr. Subedi specializes in the development of analytical methods to analyze chemical contaminants in water and will discuss the application of these methods toward quantifying illicit drug use within communities.

The following week, on Tuesday February 27, an ACS “program-in-a-box” event Opiods: Fighting Addiction With Chemistry will take place.  This topic is incredibly timely, and the program promises to be engaging and informative.  Dr. Rebecca Brown will be hosting at WKTCC in Paducah, KY, and Drs. Abigail Shelton and Robbie Montgomery will be hosting at UTM in Martin, TN.  If you would like to attend, please contact one of them for more details.

Kind regards,

~ Dr. Genessa Smith, Chair

January 2018 – Message from the Chair

Greetings KLS Members! With the turning of the calendar from 2017 to 2018, we once again find ourselves in a new year of KLS programming and leadership. Please join me in welcoming Kevin Revell as our new chair-elect. Kevin is already hard at work planning the spring program—stay tuned for more details!

This month’s speaker—Dr. Kevin Miller—is one of our own and I know that you won’t want to miss the opportunity to come hear why he was selected for the 2017 KLS Outstanding Professional Member Award. Dr. Miller specializes in organic and polymer chemistry at Murray State University and will be talking about applications of dynamic bonds in polymers.

As we enter the new year, I’d especially like to encourage you to be proactive in your KLS involvement. Whether that looks like attending monthly meetings, participating in committee work, helping with the kids’ science centers, fostering interest in National Chemistry Week, or designing a completely new KLS activity—opportunities abound! If you are particularly ambitious, you can spearhead an application for up to $3,500 in ACS funding through the Innovative Project Grant program. Application deadlines occur twice yearly: January 18th and June 30th.

Best wishes for a wonderful start to 2018.

~Genessa, KLS Chair